Putting one pill is very important. Sometimes even 2 if you anticipate your opponent will guess the bluff.
This is very important for attack manipulation clans.
The best way to use them is to wait until the last 2 turns, that is when the magic happens.
Attack manipulation is a huge advantage in low-pill battles. People tend to use cards like Brittany
near the beginning as a bluff and force your opponent to waste pills. WRONG!
Let's say Bangers
bonus is profitable after 4 pills.
So in the beginning when pills are plentiful. It is better not to pill but bluff.
Near the end, rounds 3-4, one pill can matter a lot, especially if its a low pill battle.
Your opponent used some pills, you have say a 2 pill advantage because you've bluffed the first 2 rounds.
6 pills to 4 pills. Actually, its 8 pills to 4 pills because of your bonus. A completely dominant pills amount.
That is why cards with both Attack Manipulation and DR are one of the greatest combos. Helping you get over the first 2 turns relatively unscathed.
People say Fabio
is better than Spiaghi
I say otherwise.
With attack manipulation: Good players win in 2 rounds, The best players win in 4.
P.S. 1200 words, quite long so thanks for reading.