Actually, the best counter against Jackie is 5-pilling something that can reasonably stand up to her (Ghumbo, Selma, GraksmxxT, etc.). Most Jackie players tend to play 3-4 pills since they don't expect you to stand up to her. It's only good against decent players, though. Good players can see right through that :P
Dorian 3*, Tyd, Glosh, Vinnie, Lyse Teria Cr, Azgroth, Tanaereva, Hikiyousan, Greow, Zatman, Janice, Eyrton are some examples of cards that can face her on equal footing.
(Notice how short my list is... if it were any other card I could think of at least 30, including the Big Five aside from Lyse Teria Cr. Jackie and Zatman were so broken that they ruined Uppers, IMO.)
I normally just take the damage and abuse the person through the next few rounds.
I call it activating adrenaline.
Jackie could nver be encountered after all shes got the power and bonus to protect that and even if you use damage ruduction she still can fury if the owner of that card knows how to use the pillz on her