Drawing both bonuses, I generally look to play the lower damage Freaks card first (who at this point still has a very good potential). Whether I pill conservatively or not depends on my opponent's hand (you'll get a feel for it).
If you win, then you got poison in. If you lost then hopefully you can use the pill advantage and Sheryl's ability to give yourself a good margin to hit with Sheryl whilst still keeping you in a good position.
As you play more you'll get a better idea of what to play in certain situations and hopefully make good judgement calls.
Thanks..and thanks for the list..i just found out what was missing...a finish line card..i usually get the poison in and Ector's ability..most of the time leaving my opponent down to a 3...and in the end recovering..yeah still getting the feel for it..
another question..kinda out of topic...about Ld missions...do I have to finish Bonnie's missions in order?