Hello there! I recently started the game as Piranas because of the artwork mainly, though quickly got bored of it. Recently, I bought a few things from the shop and managed to build a GHEIST deck with a few expensive cards (XU52, Wardom). I really loved GHEIST, thing is I really hated the style of artwork they did on some cards (Dolly, Dr.Saw). I just sold all my GHEIST cards for a Skeelz deck. Thing is though, none of them really fitted my playing style. Everytime I switch clans, I always think about switching back. My planning style is outpilling the opponent mainly by bluffing a lot, then end the game with a KO. Which clan fits this style.
Uppers is great for that IMO. Their abilities are great and the opponent will think your bluffing a lot of the time. Added with the bonus, even if you both 1 pill you'll most likely win. Paired with 6 damage you have a VERY quick game on your hands with 2HKO's around every corner.
Of course I'm biased though and everyone will have their own opinion