No doubt Uranus is a great card. Good is an understatement.
The card has the best DR ability in the game along with Graksmxxt and for 3 stars.
And yes Uranus wins rounds..game-ending card actually because it is that good as a finisher when your opponent is already down to 5 life or less. Inexperienced players would often see the card as a DR and just pill less or not pill at all, often they would not think of it as a finisher. Experienced players would think what if this card is actually already going for the kill? Countless times has this card already been used as a game-ender.
Low power damage reduces are okay in general, they're there simple for the DR
The thing about Uranus is...her DR is damn good, -5 min 1 is insane, and she's a 3 star - People splash Spiaghi, a -3 min 1 2 star card, Uranus is similar, although she has lower power, so she needs her bonus to be a threat, so you don't see her splashed that often.
But with her bonus, she goes from a damn good DR to a damn good bluff - she has 5 damage, no one wants that. Plus her bonus forces you to pill. So do you pill 2-3 pills just for 1 damage? What if they pill hard on Uranus, did you expect that 5 damage? You're screwed either way.
Granted, with the increasing number of -life abilities seen over the past half year (Ector, Berserk clan more recently), she isn't as dominant as she used to be, but she is still an excellent card. If Sakrohm wasn't as weak to SoA as it is, we'd probably see a lot more bans on her.