5 Uppers and 3 Skeelz- Yes, that's the correct balance.
Redra- Yes, she is the 2* DR that Uppers need.
Oxen, Rubie, Nellie- Yes, those are the staples in Uppers.
Greem- how compatible is she with Oxen? Much as I dislike Jay, perhaps Jay would be a better complement to Uppers, especially since your preset doesn't have Chiara.
Burt- He doesn't help you 2HKO. Uppers DR are dead weight against GHEIST.
Frankie Hi- Isn't he worse than Harold in just about every case? And you have plenty of characters to play on 1st.
Danae: Isn't she completely worse than Harold as well?
The problem with the Skeelz complement is that Skeelz don't have too many standout characters against the bad Uppers match ups (GHEIST and All- Stars). The 2 clans have opposite strategies- Uppers win on 2HKO and Skeelz win on gap. I find Vortex to be a much more synergestic complement to Uppers. If you stay with Skeelz, you should have either Chiara or Jay.