I love Varoslav.
He can over pill to get the poison going and you will also make the pill gap on your opponent smaller.. plus a great bluff too -2 pillz plus his low min make him good but people like solid stats better I think..
Hindelga is the best 5* that is easily affordable
baldovino is good but hindelga is better. Hindelga is better at winning rounds and has the bonus of having dr as well.
If I'm on reprisal i would open with hindelga but otherwise liona, matriochka shazam are good openers