Play fast..... i am personally amazed by the number of players with serious DT decks.. uppers monty with jackie and zatman etc.. yet they play really really slow. dont like facing them coz 1 you dont score big vs them. and 2, you can lose to them so you score even lower
two DT decks should have one and the same goal.. finish that match ASAP take your points and move on.
as for maxing points when u are losing, load up the pillz on your lowest star card and take down that 5 star beast.
Its partly luck which you can't change. when I say luck I mean whether your opponent is fast or slow, how many reducers they got etc.
Other than luck you gotta look at star count and pill management. Lower star decks score higher, but dont go so low that you always end up playing all 4 rounds. also try and finish with a few pillz atleast. you get extra points if you finish with pillz left over or score a K.O.